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Article

DNA Methylation Levels of Melanoma Risk Genes Are Associated with Clinical Characteristics of Melanoma Patients.

BioMed research international - 1 Jan 2015

de Araújo Érica S S, Pramio Dimitrius T, Kashiwabara André Y, Pennacchi Paula C, Maria-Engler Silvya S, Achatz Maria I, Campos Antonio H J F M, Duprat João P, Rosenberg Carla, Carraro Dirce M, Krepischi Ana C V

Abstract excerpt

In melanoma development, oncogenic process is mediated by genetic and epigenetic mutations, and few studies have so far explored the role of DNA methylation either as predisposition factor or biomarker. We tested patient samples for germline CDKN2A methylation status and found no evidence of inactivation by promoter hypermethylation. We have also investigated the association of clinical characteristics of samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26106605
DOI: 10.1155/2015/376423
PMCID: PMC4461735

Genes

MGMT
MITF
BAP1
KIT
PALB2
POT1
TERT
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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