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Article

Copy number variations in DCC/18q and ERBB2/17q are associated with disease-free survival in microsatellite stable colon cancer.

International journal of cancer - 1 Apr 2017

Sefrioui David, Vermeulin Thomas, Blanchard France, Chapusot Caroline, Beaussire Ludivine, Armengol-Debeir Laura, Sesboué Richard, Gangloff Alice, Hebbar Mohamed, Copin Marie-Christine, Houivet Estelle, Schwarz Lilian, Clatot Florian, Tuech Jean-Jacques, Bénichou Jacques, Martin Laurent, Bouvier Anne-Marie, Sabourin Jean-Christophe, Sarafan-Vasseur Nasrin, Frébourg Thierry, Lepage Côme, Michel Pierre, Di Fiore Frédéric

Abstract excerpt

We conducted a prospective study to assess the prognostic impact of selected copy number variations (CNVs) in Stage II-III microsatellite stable (MSS) colon cancer. A total of 401 patients were included from 01/2004 to 01/2009. The CNVs in 8 selected target genes, DCC/18q, EGFR/7p, TP53/17p, BLK/8p, MYC/8q, APC/5q, ERBB2/17q and STK6/20q, were detected using a quantitative multiplex polymerase chain reaction of...

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Source

Identifiers

PMID: 28006840
DOI: 10.1002/ijc.30584

Genes

DCC
ERBB2
APC
BLK
EGFR
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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