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Article

The Central Role of KNG1 Gene as a Genetic Determinant of Coagulation Pathway-Related Traits: Exploring Metaphenotypes.

PloS one - 1 Jan 2016

Brunel Helena, Massanet Raimon, Martinez-Perez Angel, Ziyatdinov Andrey, Martin-Fernandez Laura, Souto Juan Carlos, Perera Alexandre, Soria José Manuel

Abstract excerpt

Traditional genetic studies of single traits may be unable to detect the pleiotropic effects involved in complex diseases. To detect the correlation that exists between several phenotypes involved in the same biological process, we introduce an original methodology to analyze sets of correlated phenotypes involved in the coagulation cascade in genome-wide association studies. The methodology consists of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 28005926
DOI: 10.1371/journal.pone.0167187
PMCID: PMC5178993

Genes

KNG1
FETUB
HRG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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