Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human population-specific gene expression and transcriptional network modification with polymorphic transposable elements.

Nucleic acids research - 17 Mar 2017

Wang Lu, Rishishwar Lavanya, Mariño-Ramírez Leonardo, Jordan I King

Abstract excerpt

Transposable element (TE) derived sequences are known to contribute to the regulation of the human genome. The majority of known TE-derived regulatory sequences correspond to relatively ancient insertions, which are fixed across human populations. The extent to which human genetic variation caused by recent TE activity leads to regulatory polymorphisms among populations has yet to be thoroughly explored. In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Black People
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Genetic Loci

Share to Immunity, Innate

Share to PAX5 Transcription Factor

Share to Receptors, Antigen, T-Cell

Source

Open in PubMed Open full text

Identifiers

PMID: 27998931
DOI: 10.1093/nar/gkw1286
PMCID: PMC5389732

Genes

PAX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human population-specific gene expression and transcriptional network modification with polymorphic transposable elements.PMID 27998931Read ↗

Contribution of unfixed transposable element insertions to human regulatory variationSemantic proximity Read ↗

Atlas of transcriptionally active transposable elements in human adult tissuesSemantic proximity Read ↗

Functional disease architectures reveal unique biological role of transposable elementsSemantic proximity Read ↗

Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissuesSemantic proximity Read ↗

Long-range regulatory effects of Neandertal DNA in modern humansSemantic proximity Read ↗

Patterns of cis regulatory variation in diverse human populations.Semantic proximity Read ↗

Regulatory Transposable Elements in the Encyclopedia of DNA ElementsSemantic proximity Read ↗

Expression quantitative trait loci (eQTL): from population genetics to precision medicine.Semantic proximity Read ↗

Genome-wide analysis of the association of transposable elements with gene regulation suggests that <i>Alu</i> elements have the largest overall regulatory impactSemantic proximity Read ↗

The transposable element environment of human genes is associated with histone and expression changes in cancer.Semantic proximity Read ↗

Transposable elements impact the human regulatory landscape through cell type specific epigenomic associationsSemantic proximity Read ↗

Unraveling transposable element-mediated regulatory landscape in diverse human immune cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.