Article

Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

2020-05-25

Abstract excerpt

<h4>Background</h4> Mobile elements are a major source of human structural variants and some mobile elements can regulate gene expression and alternative splicing. However, the impact of polymorphic mobile element insertions (pMEIs) on gene expression and splicing in diverse human tissues has not been thoroughly studied. The multi-tissue gene expression and whole genome sequencing data generated by the Genotype-T...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 660a3b9c-aaaf-55e3-ac53-ff771c95ff14
DOI: 10.1101/2020.05.23.111310

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissuesDOI 10.1101/2020.05.23.111310Read

Structural variants are a major source of gene expression differences in humans and often affect multiple nearby genesSemantic proximity Read

Mobile elements in human population-specific genome and phenotype divergenceSemantic proximity Read

Contribution of unfixed transposable element insertions to human regulatory variationSemantic proximity Read

Mobile element variation contributes to population-specific genome diversification, gene regulation and disease risk.Semantic proximity Read

eQTL mapping identifies insertion- and deletion-specific eQTLs in multiple tissues.Semantic proximity Read

Alternative splicing is coupled to gene expression in a subset of variably expressed genesSemantic proximity Read

Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differencesSemantic proximity Read

Atlas of transcriptionally active transposable elements in human adult tissuesSemantic proximity Read

Extensive genomic and transcriptional diversity identified through massively parallel DNA and RNA sequencing of eighteen Korean individuals.Semantic proximity Read

Identification and analysis of splicing quantitative trait loci across multiple tissues in the human genomeSemantic proximity Read

Identification and analysis of splicing quantitative trait loci across multiple tissues in the human genome.Semantic proximity Read

The impact of structural variation on human gene expressionSemantic proximity Read