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Article

Relationship Between ABCB1 Polymorphisms and Cold Pain Sensitivity Among Healthy Opioid-naive Malay Males.

Pain practice : the official journal of World Institute of Pain - 1 Sept 2017

Zahari Zalina, Lee Chee Siong, Ibrahim Muslih Abdulkarim, Musa Nurfadhlina, Mohd Yasin Mohd Azhar, Lee Yeong Yeh, Tan Soo Choon, Mohamad Nasir, Ismail Rusli

Abstract excerpt

BACKGROUND: Endogenous and exogenous opioids are substrates of the permeability glycoprotein (P-gp) efflux transporter, which is encoded by the ABCB1 (MDR1) gene. Genetic polymorphisms of ABCB1 may contribute to interindividual differences in pain modulation and analgesic responses. We investigated the relationship between ABCB1 polymorphisms and cold pain sensitivity among healthy males. METHODS: Cold pain...

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Topics

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Share to Analgesics, Opioid
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27996183
DOI: 10.1111/papr.12546

Genes

ABCB1

Variants

rs1128503
rs2032582

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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