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Article

Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants.

British journal of clinical pharmacology - 1 Jun 2017

Sohn Jin A, Kim Han-Suk, Oh Jaeseong, Cho Joo-Youn, Yu Kyung-Sang, Lee Juyoung, Shin Seung Han, Lee Jin A, Choi Chang Won, Kim Ee-Kyung, Kim Beyong Il, Park Eun Ae

Abstract excerpt

AIMS: The purpose of this study was to explore clinical markers reflecting developmental changes in drug clearance by preterm infants. METHODS: Preterm infants administered aminophylline or theophylline to treat apnoea of prematurity were enrolled in this study. Trough and one of 2 h, 4 h or 6 h post-dose blood samples and urine samples were collected during steady state, to determine the concentrations of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27995649
DOI: 10.1111/bcp.13211
PMCID: PMC5427230

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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