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Article

Combination analysis of NOS3, ABCB1 and IL23R polymorphisms with alcohol-induced osteonecrosis of the femoral head risk in Chinese males.

Oncotarget - 16 May 2017

Wang Yuan, Yang Xuejun, Shi Jianping, Zhao Yan, Pan Linlin, Zhou Jinqiu, Wang Guoqiang, Wang Jianzhong

Abstract excerpt

BACKGROUND: Common variants of multiple genes played a crucial role in osteonecrosis of the femoral head (ONFH) onset which was proved by many previous reports. We hypothesized that polymorphisms in NOS3, ABCB1 and IL23R were related to individual differences in alcohol sensitivity and the development of alcohol-induced ONFH. METHODS: In this case-control study, we evaluated 8 SNPs in three genes in the Chinese...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28422712
DOI: 10.18632/oncotarget.16809
PMCID: PMC5464910

Genes

NOS3
ABCB1

Provenance

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