Article
Performance of Celera RUO integrase resistance assay across multiple HIV-1 subtypes.
Journal of virological methods - 1 Mar 2017
Wallis Carole L, Viana Raquel V, Saravanan Shanmugam, Silva de Jesus Carlos, Zeh Clement, Halvas Elias K, Mellors John W
Abstract excerpt
BACKGROUND: HIV-1 sequence variation is a major obstacle to developing molecular based assays for multiple subtypes. This study sought to independently assess performance characteristics of the ViroSeq™ HIV-1 Integrase RUO Genotyping Kit (Celera, US) for samples of multiple different HIV-1 subtypes. METHODS: 264 samples were tested in the validation, 106 from integrase inhibitor naïve patients' sent for routine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
