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Article

Glucose Tolerance, MTHFR C677T and NOS3 G894T Polymorphisms, and Global DNA Methylation in Mixed Ancestry African Individuals.

Journal of diabetes research - 1 Jan 2016

Matsha Tandi E, Pheiffer Carmen, Mutize Tinashe, Erasmus Rajiv T, Kengne Andre P

Abstract excerpt

The aim of this study is to quantify global DNA methylation and investigate the relationship with diabetes status and polymorphisms in MTHFR C677T and NOS3 G894T genes in mixed ancestry subjects from South Africa. Global DNA methylation was measured, and MTHFR rs1801133 and NOS3 rs1799983 polymorphisms were genotyped using high throughput real-time polymerase chain reaction and direct DNA sequencing. Of the 564...

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Source

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Identifiers

PMID: 27990443
DOI: 10.1155/2016/8738072
PMCID: PMC5136398

Genes

NOS3
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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