Article
Association between the MTNR1B, HHEX, SLC30A8, and TCF7L2 single nucleotide polymorphisms and cardiometabolic risk profile in a mixed ancestry South African population.
Scientific reports - 10 Oct 2023
Ngwa Ndonwi Elvis, Matshazi Don Makwakiwe, Davison Glenda Mary, Kengne Andre Pascal, Matsha Tandi Edith
Abstract excerpt
Single nucleotide polymorphisms of the TCF7L2, HHEX, SLC30A8, MTNR1B, SLC2A2 and GLIS3 genes are well established candidate genes for cardiometabolic diseases (CMDs) across different ethnic populations. We investigated their association with CMDs in a mixed ancestry population of South Africa. rs10830963, rs1111875, rs11920090, rs13266634, rs7034200 and SNPs were genotyped by quantitative real time PCR...