Article
Mutations in basal core promoter is associated with significant fibrosis in both HBeAg positive and negative treatment-naïve chronic hepatitis B.
Clinics and research in hepatology and gastroenterology - 1 Jun 2017
Yan Li-Bo, Zhu Xia, Bai Lang, Tang Xiao-Qiong, Du Ling-Yao, Chen En-Qiang, Liang Ling-Bo, Tang Hong
Abstract excerpt
AIM: Assessment of liver fibrosis is important for the decision of whether to administrate antiviral treatment in chronic Hepatitis B (CHB) patients. The objective was to investigate the relationship between clinical factors and fibrosis, identify predictors of significant fibrosis in Chinese CHB patients. METHODS: Two hundred and seventy-four treatment-naïve CHB patients (208 HBeAg-positive and 66...
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