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Article

Efficient genome editing of differentiated renal epithelial cells.

Pflugers Archiv : European journal of physiology - 1 Feb 2017

Hofherr Alexis, Busch Tilman, Huber Nora, Nold Andreas, Bohn Albert, Viau Amandine, Bienaimé Frank, Kuehn E Wolfgang, Arnold Sebastian J, Köttgen Michael

Abstract excerpt

Recent advances in genome editing technologies have enabled the rapid and precise manipulation of genomes, including the targeted introduction, alteration, and removal of genomic sequences. However, respective methods have been described mainly in non-differentiated or haploid cell types. Genome editing of well-differentiated renal epithelial cells has been hampered by a range of technological issues, including...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27987038
DOI: 10.1007/s00424-016-1924-4
PMCID: PMC5222933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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