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Article

A Two-Gene Blood Test for Methylated DNA Sensitive for Colorectal Cancer

30 Apr 2015

Abstract excerpt

BACKGROUND: Specific genes are methylated with high frequency in colorectal neoplasia, and may leak into blood. Detection of multiple methylated DNA biomarkers in blood may improve assay sensitivity for colorectal cancer (CRC) relative to a single marker. We undertook a case-control study evaluating the presence of two methylation DNA markers, BCAT1 and IKZF1, in circulation to determine if they were...

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Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
Share to Genetic factors in colorectal cancer

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PMID: 25928810
DOI: 10.1371/journal.pone.0125041

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