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Article

Additive Interaction of MTHFR C677T and MTRR A66G Polymorphisms with Being Overweight/Obesity on the Risk of Type 2 Diabetes.

International journal of environmental research and public health - 15 Dec 2016

Zhi Xueyuan, Yang Boyi, Fan Shujun, Li Yongfang, He Miao, Wang Da, Wang Yanxun, Wei Jian, Zheng Quanmei, Sun Guifan

Abstract excerpt

Although both methylenetetrahydrofolate reductase (MTHFR) C677T and methionine synthase reductase (MTRR) A66G polymorphisms have been associated with type 2 diabetes (T2D), their interactions with being overweight/obesity on T2D risk remain unclear. To evaluate the associations of the two polymorphisms with T2D and their interactions with being overweight/obesity on T2D risk, a case-control study of 180 T2D...

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Source

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Identifiers

PMID: 27983710
DOI: 10.3390/ijerph13121243
PMCID: PMC5201384

Genes

MTHFR
MTRR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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