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Article

The relationship between of ACE I/D and the MTHFR C677T polymorphisms in the pathophysiology of type 2 diabetes mellitus in a population of Brazilian obese patients.

Archives of endocrinology and metabolism - 1 Feb 2018

Pirozzi Flavio Fontes, Belini Junior Edis, Okumura Jessika Viviani, Salvarani Mariana, Bonini-Domingos Claudia Regina, Ruiz Milton Artur

Abstract excerpt

Objectives This study aimed to evaluate the frequencies of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) and methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphisms in obese patients with and without type 2 diabetes mellitus (T2DM). Subjects and methods These polymorphisms were analyzed by polymerase chain reaction in 125 patients with obesity, 47 (T2DM) and 78 (Control...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Mutagenesis, Insertional

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Share to Peptidyl-Dipeptidase A

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Source

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Identifiers

PMID: 29694640
DOI: 10.20945/2359-3997000000005
PMCID: PMC10118689

Genes

ACE
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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