Article
Knowledge insufficient: the management of haemoglobin SC disease.
British journal of haematology - 1 Feb 2017
Pecker Lydia H, Schaefer Beverly A, Luchtman-Jones Lori
Abstract excerpt
Although haemoglobin SC (HbSC) accounts for 30% of sickle cell disease (SCD) in the United States and United Kingdom, evidence-based guidelines for genotype specific management are lacking. The unique pathology of HbSC disease is complex, characterized by erythrocyte dehydration, intracellular sickling and increased blood viscosity. The evaluation and treatment of patients with HbSC is largely inferred from...
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