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Current and emerging treatments for sickle cell disease

28 Aug 2019

Abstract excerpt

Sickle cell disease (SCD) is a group of inherited blood disorders affecting the hemoglobin, shortening the lifespan of erythrocytes, and causing them to take on a distinctive sickled shape that can lead to vaso-occlusion. Current treatment aims to reduce morbidity and mortality through hydroxyurea, erythrocyte transfusion, and hematopoietic stem cell transplantation. This article reviews the disease process,...

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PMID: 31460979
DOI: 10.1097/01.jaa.0000578812.47138.99

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