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Article

Is There a Difference in Occurrence of Complications Between Adults With Hemoglobin SS and Hemoglobin SC Disease: An Extended Systematic Review.

European journal of haematology - 1 Oct 2026

van der Meer Martijn, Velsink Kim, Tong Wing H, Schoones Jan W

Abstract excerpt

Sickle cell disease (SCD) is characterized by both acute and chronic complications. The clinical manifestation of these complications differs between genotypes. Given the large amount of research already published, this systematic review aims to offer a complete overview of types of sickle cell complications between adults in the most common genotypes Hemoglobin SS (HbSS) and Hemoglobin SC (HbSC), putting options...

Read the complete abstract on PubMed

Topics

Humans
Hemoglobin SC Disease
Anemia, Sickle Cell
Hemoglobin, Sickle
Vaso-Occlusive Crises
Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adult

Disease Susceptibility

Source

Open in PubMed Open full text

Identifiers

PMID: 42297565
DOI: 10.1111/ejh.70239
PMCID: PMC13542954

Genes

SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

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