Concordance between immunohistochemistry and MSI analysis for detection of MMR/MSI status in colorectal cancer patients

doi:10.1186/s13000-024-01571-5

Article

Concordance between immunohistochemistry and MSI analysis for detection of MMR/MSI status in colorectal cancer patients

28 Nov 2024

Abstract excerpt

BACKGROUND: Recently, screening of colorectal cancer (CRC) patients for mismatch repair/microsatellite instability (MMR/MSI) status is widely practiced due to its potential predictive and prognostic roles and a screening tool to reveal Lynch Syndrome (LS). The purpose of the study was to evaluate concordance between immunohistochemistry (IHC) and MSI analysis methods for detection of MMR/MSI status in colorectal...

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