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Article

Uremic Serum Impairs Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stromal Cells.

Journal of cellular physiology - 1 Aug 2017

Della Bella Elena, Pagani Stefania, Giavaresi Gianluca, Capelli Irene, Comai Giorgia, Donadei Chiara, Cappuccilli Maria, La Manna Gaetano, Fini Milena

Abstract excerpt

Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) is characterized by an increased fracture risk. Bone marrow mesenchymal stromal cells (BMSCs) may be involved in the pathogenesis of bone disease and, in view of their promising potential applications in bone tissue engineering, the effect of uremia on BMSCs regenerative potential represents a central issue. The present study evaluated in vitro the effect...

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PMID: 27976811
DOI: 10.1002/jcp.25732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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