Article
Spontaneous Coronary Artery Dissection and a Family History of Aortic Dissection: A Genetic Association Study.
Journal of the American Heart Association - 15 Apr 2025
McGrath-Cadell Lucy, Hesselson Stephanie, Tarr Ingrid, Rath Emma M, Troup Michael, Gao Yunkai, Junday Keerat, Bax Monique, Iismaa Siiri E, Collins Nicholas, Muller David W M, Kovacic Jason C, Giannoulatou Eleni, Graham Robert M
Abstract excerpt
BACKGROUND: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome or sudden cardiac death, primarily affecting relatively young women (median age, 51 years) without typical cardiovascular risk factors. SCAD has a genetic component, with genome-wide association studies identifying multiple risk loci. Thoracic aortic dissection (type A) shares some genetic...
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