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Article

99-Case Study of Sporadic Aortic Dissection by Whole Exome Sequencing Indicated Novel Disease-Associated Genes and Variants in Chinese Population.

BioMed research international - 1 Jan 2020

Wang Zanxin, Zhuang Xianmian, Chen Bailang, Wen Junmin, Peng Fang, Liu Xiling, Wei Minxin

Abstract excerpt

BACKGROUND: In this study, the whole exome sequencing in human aortic dissection, a highly lethal cardiovascular disease, was investigated to explore the aortic dissection-associated genes and variants in Chinese population. METHODS: Whole exome sequencing was performed in 99 cases of aortic dissection. All single nucleotide polymorphisms (SNPs), insertions/deletions (InDels), and copy number variations (CNVs)...

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Share to Aortic Aneurysm, Thoracic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33083483
DOI: 10.1155/2020/7857043
PMCID: PMC7556049

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