Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic Flux

1 Dec 2016

Abstract excerpt

Adaptive immunity requires the generation of memory T cells from naive precursors selected in the thymus. The key intermediaries in this process are stem cell-like memory T (T SCM ) cells, multipotent progenitors that can both self-renew and replenish more differentiated subsets of memory T cells. In theory, antigen specificity within the T SCM pool may be imprinted statically as a function of largely dormant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27974195
DOI: 10.1016/j.celrep.2016.11.037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Stem Cell-like Memory T Cells Are Maintained in a State of Dynamic FluxPMID 27974195Read ↗

In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells.Semantic proximity Read ↗

Phenotypic and Immunometabolic Aspects on Stem Cell Memory and Resident Memory CD8+ T Cells.Semantic proximity Read ↗

Rapid turnover of effector-memory CD4(+) T cells in healthy humans.Semantic proximity Read ↗

Uneven distributions of naïve and memory T cells in the CD4 and CD8 T-cell populations derived from a single stem cell in an atomic bomb survivor: implications for the origins of the memory T-cell pools in adulthood.Semantic proximity Read ↗

Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection.Semantic proximity Read ↗

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory.Semantic proximity Read ↗

Direct measurement of T cell subset kinetics in vivo in elderly men and women.Semantic proximity Read ↗

Impact of human CD8+ T cell senescence on<sup>89</sup>Zr radiolabelling and homing propertiesSemantic proximity Read ↗

Quantification of T‐cell dynamics: from telomeres to DNA labelingSemantic proximity Read ↗

Impact of human CD8+ T cell senescence on 89Zr radiolabelling and homing propertiesSemantic proximity Read ↗

Cell-density independent increased lymphocyte production and loss rates post-autologous hematopoietic stem cell transplantationSemantic proximity Read ↗

Turnover of naive- and memory-phenotype T cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.