Article
Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration.
Proceedings of the National Academy of Sciences of the United States of America - 2 Apr 2002
Kim Hyung-Suk, Lee Gene, John Simon W M, Maeda Nobuyo, Smithies Oliver
Abstract excerpt
The angiotensinogen M235T polymorphism in humans is linked to differential expression of the human angiotensinogen gene (AGT) gene and hypertension, but the homeostatic responses resulting from this polymorphism are not known. We therefore investigated how mice respond to five genetically determi...
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