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Coronary Artery Disease Genetics Enlightened by Genome-Wide Association Studies

1 Jul 2021

Abstract excerpt

Many cardiovascular diseases are facilitated by strong inheritance. For example, large-scale genetic studies identified hundreds of genomic loci that affect the risk of coronary artery disease. At each of these loci, common variants are associated with disease risk with robust statistical evidence but individually small effect sizes. Only a minority of candidate genes found at these loci are involved in the...

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PMID: 34368511
DOI: 10.1016/j.jacbts.2021.04.001

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