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Article

Latent TGF-β binding protein-1 deficiency decreases female fertility.

Biochemical and biophysical research communications - 22 Jan 2017

Dietzel Eileen, Weiskirchen Sabine, Floehr Julia, Horiguchi Masahito, Todorovic Vesna, Rifkin Daniel B, Jahnen-Dechent Willi, Weiskirchen Ralf

Abstract excerpt

The four latent transforming growth factor-β (TGF-β) binding proteins LTBP1-4 are extracellular matrix-associated proteins playing a critical role in the activation of TGF-β. The LTBP1 gene forms two major transcript variants (i.e. Ltbp1S and Ltbp1L) that are derived from different promoters. We have previously shown the importance of LTBP1 in vivo by using three different Ltbp1 null mice that were either deleted...

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Source

Identifiers

PMID: 27956181
DOI: 10.1016/j.bbrc.2016.12.046

Genes

LTBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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