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Article

Transforming growth factor beta (TGFbeta1, TGFbeta2 and TGFbeta3) null-mutant phenotypes in embryonic gonadal development.

Molecular and cellular endocrinology - 6 Nov 2008

Memon Mushtaq A, Anway Matthew D, Covert Trevor R, Uzumcu Mehmet, Skinner Michael K

Abstract excerpt

The role transforming growth factor beta (TGFb) isoforms TGFb1, TGFb2 and TGFb3 have in the regulation of embryonic gonadal development was investigated with the use of null-mutant (i.e. knockout) mice for each of the TGFb isoforms. Late embryonic gonadal development was investigated because homozygote TGFb null-mutant mice generally die around birth, with some embryonic loss as well. In the testis, the TGFb1...

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Identifiers

PMID: 18790002
DOI: 10.1016/j.mce.2008.08.017
PMCID: PMC2593935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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