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Article

Genotype-Specific Interaction of Latent TGFβ Binding Protein 4 with TGFβ.

PloS one - 1 Jan 2016

Lamar Kay-Marie, Miller Tamari, Dellefave-Castillo Lisa, McNally Elizabeth M

Abstract excerpt

Latent TGFβ binding proteins are extracellular matrix proteins that bind latent TGFβ to form the large latent complex. Nonsynonymous polymorphisms in LTBP4, a member of the latent TGFβ binding protein gene family, have been linked to several human diseases, underscoring the importance of TGFβ regulation for a range of phenotypes. Because of strong linkage disequilibrium across the LTBP4 gene, humans have two main...

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Identifiers

PMID: 26918958
DOI: 10.1371/journal.pone.0150358
PMCID: PMC4769137

Genes

LTBP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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