Article
Allele rs2010963 C of the VEGFA gene is associated with the decreased risk of primary varicose veins in ethnic Russians.
Phlebology - 1 Feb 2018
Shadrina Alexandra S, Smetanina Mariya A, Sokolova Ekaterina A, Shamovskaya Darya V, Sevost'ianova Kseniya S, Shevela Andrey I, Soldatsky Evgenii Y, Seliverstov Evgenii I, Demekhova Marina Y, Shonov Oleg A, Ilyukhin Evgeny A, Voronina Elena N, Pikalov Ilya V, Zolotukhin Igor A, Kirienko Alexander I, Filipenko Maxim L
Abstract excerpt
Objective To study the association of polymorphisms rs699947, rs2010963, rs3025039 in the VEGFA gene region and rs1870377, rs2305949, in the VEGFR2 gene region with the risk of primary varicose veins in ethnic Russians. Methods Genotypes were determined by real-time PCR allelic discrimination. The case group consisted of 448 patients with primary varicose veins and the control group comprised 609...