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Article

Polymorphisms in inflammation-related genes and the risk of primary varicose veins in ethnic Russians.

Immunologic research - 1 Feb 2018

Shadrina Alexandra, Voronina Elena, Smetanina Mariya, Tsepilov Yakov, Sevost'ianova Kseniya, Shevela Andrey, Seliverstov Evgenii, Zakharova Elena, Ilyukhin Evgeny, Kirienko Alexander, Zolotukhin Igor, Filipenko Maxim

Abstract excerpt

Inflammation was shown to be activated in varicose veins, although its role in the development of vein wall transformation remains inconclusive. We aimed to investigate the influence of 13 inflammation-related single nucleotide polymorphisms (SNPs) TNF rs1800629 and rs3093661, IL1A rs1800587, IL1RN rs4251961, IL6 rs1800795 and , IFNG , IL10 , TGFB1 , HIF1A , NFKB1...

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Identifiers

PMID: 29247331
DOI: 10.1007/s12026-017-8981-4

Genes

TNF
NFKB1
IFNG
TGFB1

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