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Article

Polymorphisms in the MTHFR and MTR genes and the risk of varicose veins in ethnical Russians.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Nov 2016

Shadrina Alexandra Sergeevna, Sevost'ianova Kseniya Sergeevna, Shevela Andrey Ivanovich, Soldatsky Evgenii Yurievich, Seliverstov Evgenii Igorevich, Demekhova Marina Yurievna, Shonov Oleg Aleksandrovich, Ilyukhin Evgenii Arkadievich, Smetanina Mariya Aleksandrovna, Voronina Elena Nikolaevna, Pikalov Ilya Victorovich, Zolotukhin Igor Anatolyevich, Filipenko Maxim Leonidovich

Abstract excerpt

OBJECTIVES: The objective of this study was to study the association of polymorphisms MTHFR C677T (rs1801133) and MTR A2756G (rs1805087) with the risk of varicose veins in ethnical Russians. METHODS: We genotyped 475 patients with varicose veins, 168 individual without chronic venous disease, and the population-based group of 896 subjects. Association was studied using logistic regression analysis adopting...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Ethnicity
Share to Inheritance Patterns
Share to Logistic Models
Share to Methylenetetrahydrofolate Reductase (NADPH2)
Share to Polymorphism, Single Nucleotide
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Source

Identifiers

PMID: 27097558
DOI: 10.3109/1354750X.2016.1171902

Genes

MTHFR
MTR

Variants

rs1801133
rs1801133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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