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Article

Genome-wide association study in ethnic Russians suggests an association of the MHC class III genomic region with the risk of primary varicose veins.

Gene - 15 Jun 2018

Shadrina Alexandra, Tsepilov Yakov, Sokolova Ekaterina, Smetanina Mariya, Voronina Elena, Pakhomov Eugene, Sevost'ianova Kseniya, Shevela Andrey, Ilyukhin Evgeny, Seliverstov Evgeny, Zolotukhin Igor, Filipenko Maxim

Abstract excerpt

Heredity is a well-known risk factor for varicose veins, but genetic basis of this condition remains poorly studied. Our aim was to conduct a large-scale genetic association study for primary varicose veins (PVVs) in the population of ethnic Russians. An initial scan using Illumina HumanExome-12 v1.0 BeadChip was performed for 273 patients with PVVs and 250 controls without a history of chronic venous disease and...

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PMID: 29551506
DOI: 10.1016/j.gene.2018.03.039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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