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Article

Functional polymorphism rs1024611 in the MCP1 gene is associated with the risk of varicose veins of lower extremities.

Journal of vascular surgery. Venous and lymphatic disorders - 1 Jul 2017

Shadrina Alexandra S, Smetanina Mariya A, Sevost'ianova Kseniya S, Seliverstov Evgenii I, Ilyukhin Evgeny A, Voronina Elena N, Zolotukhin Igor A, Filipenko Maxim L

Abstract excerpt

OBJECTIVE: Monocyte chemoattractant protein 1 (MCP-1) is a chemokine responsible for monocyte, basophil, and T-lymphocyte attraction. Polymorphism rs1024611 located in the regulatory region of the MCP1 gene has previously been shown to be associated with increased MCP-1 production. In our study, we aimed to examine the association of rs1024611 with the risk of primary varicose veins (PVVs) of lower extremities....

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Identifiers

PMID: 28623996
DOI: 10.1016/j.jvsv.2016.12.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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