Article
Identification of a CD133-CD55- population functions as a fetal common skeletal progenitor.
Scientific reports - 8 Dec 2016
Weng Lihong, Hu Xingbin, Kumar Bijender, Garcia Mayra, Todorov Ivan, Jung Xiaoman, Marcucci Guido, Forman Stephen J, Chen Ching-Cheng
Abstract excerpt
In this study, we identified a CD105+CD90.1-CD133-CD55- (CD133-CD55-) population in the fetal skeletal element that can generate bone and bone marrow. Besides osteoblasts and chondrocytes, the CD133-CD55- common progenitors can give rise to marrow reticular stromal cells and perivascular mesenchymal progenitors suggesting they function as the fetal common skeletal progenitor. Suppression of CXCL12 and Kitl...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
