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Article

FGF8 signaling sustains progenitor status and multipotency of cranial neural crest-derived mesenchymal cells in vivo and in vitro.

Journal of molecular cell biology - 1 Oct 2015

Shao Meiying, Liu Chao, Song Yingnan, Ye Wenduo, He Wei, Yuan Guohua, Gu Shuping, Lin Congxin, Ma Liang, Zhang Yanding, Tian Weidong, Hu Tao, Chen YiPing

Abstract excerpt

The cranial neural crest (CNC) cells play a vital role in craniofacial development and regeneration. They are multi-potent progenitors, being able to differentiate into various types of tissues. Both pre-migratory and post-migratory CNC cells are plastic, taking on diverse fates by responding to different inductive signals. However, what sustains the multipotency of CNC cells and derivatives remains largely...

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Share to Cell Differentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 8

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Source

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Identifiers

PMID: 26243590
DOI: 10.1093/jmcb/mjv052
PMCID: PMC4589951

Genes

FGF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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