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Article

Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease.

Scientific reports - 8 Dec 2016

Steinacker Petra, Blennow Kaj, Halbgebauer Steffen, Shi Song, Ruf Viktoria, Oeckl Patrick, Giese Armin, Kuhle Jens, Slivarichova Dana, Zetterberg Henrik, Otto Markus

Abstract excerpt

While cerebrospinal fluid (CSF) biomarkers for Creutzfeldt-Jakob disease (CJD) are established and partly included in the diagnostic criteria, no blood biomarkers are available. Here, we assessed the utility of serum neurofilament light chain (NF-L) and tau protein in comparison to CSF markers (NF-L and phosphorylated NF heavy chain (pNF-H), tau, S100B, 14-3-3) and prion conversion assay (real-time quaking...

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Identifiers

PMID: 27929120
DOI: 10.1038/srep38737
PMCID: PMC5144074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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