Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-Speed Mouse Backcrossing Through the Female Germ Line.

PloS one - 1 Jan 2016

Grove Erin, Eckardt Sigrid, McLaughlin K John

Abstract excerpt

Transferring mouse mutations into specific mouse strain backgrounds can be critical for appropriate analysis of phenotypic effects of targeted genomic alterations and quantitative trait loci. Speed congenic breeding strategies incorporating marker-assisted selection of progeny with the highest percentage target background as breeders for the next generation can produce congenic strains within approximately 5...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Congenic
Share to Germ Cells
Share to Inbreeding

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred C57BL

Share to Phenotype

Share to Quantitative Trait Loci

Share to Reproduction

Source

Open in PubMed Open full text

Identifiers

PMID: 27926922
DOI: 10.1371/journal.pone.0166822
PMCID: PMC5142779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-Speed Mouse Backcrossing Through the Female Germ Line.PMID 27926922Read ↗

Exclusive transmission of the embryonic stem cell-derived genome through the mouse germline.Semantic proximity Read ↗

A new mouse SNP genotyping assay for speed congenics: combining flexibility, affordability, and power.Semantic proximity Read ↗

Backcrossing to Generate a Congenic Mouse Strain.Semantic proximity Read ↗

Reproductive performance primarily depends on the female genotype in a two-factorial breeding experiment using high-fertility mouse lines.Semantic proximity Read ↗

Male Infertility Is Responsible for Nearly Half of the Extinction Observed in the Mouse Collaborative Cross.Semantic proximity Read ↗

FVB/N: an inbred mouse strain preferable for transgenic analyses.Semantic proximity Read ↗

Generation of rat "supersonic" congenic/conplastic strains using superovulation and embryo transfer.Semantic proximity Read ↗

Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection.Semantic proximity Read ↗

High-speed system to generate congenic strains in medaka.Semantic proximity Read ↗

Scheduled simple production method of pseudopregnant female mice for embryo transfer using the luteinizing hormone-releasing hormone agonistSemantic proximity Read ↗

Emergency prevention of extinction of a transgenic allele in a less-fertile transgenic mouse line by crossing with an inbred or outbred mouse strain coupled with assisted reproductive technologies.Semantic proximity Read ↗

Efficient production of offspring from Japanese wild-derived strains of mice (Mus musculus molossinus) by improved assisted reproductive technologies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.