Article
FVB/N: an inbred mouse strain preferable for transgenic analyses.
Proceedings of the National Academy of Sciences of the United States of America - 15 Mar 1991
Taketo M, Schroeder A C, Mobraaten L E, Gunning K B, Hanten G, Fox R R, Roderick T H, Stewart C L, Lilly F, Hansen C T
Abstract excerpt
FVB/N mice offer a system suitable for most transgenic experiments and subsequent genetic analyses. The inbred FVB/N strain is characterized by vigorous reproductive performance and consistently large litters. Moreover, fertilized FVB/N eggs contain large and prominent pronuclei, which facilitate microinjection of DNA. The phenotype of large pronuclei in the zygote is a dominant trait associated with the FVB/N...
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