Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Backcrossing to Generate a Congenic Mouse Strain.

Cold Spring Harbor protocols - 2 Jan 2024

Papaioannou Virginia E, Behringer Richard R

Abstract excerpt

Genetic background can have subtle or profound effects on mutant phenotypes, providing additional information regarding the function of the gene. If your mutation is maintained on one genetic background but you wish to analyze it on another, it is a simple matter to transfer the mutation to a recipient strain background by repeated backcrossing (introgression) as detailed in this protocol. The resulting strain is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Laboratory
Share to Chromosomes
Share to Genome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Source

Identifiers

PMID: 37932101
DOI: 10.1101/pdb.prot108039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Backcrossing to Generate a Congenic Mouse Strain.PMID 37932101Read ↗

[Applications of congenic strains in the mouse].Semantic proximity Read ↗

Recovering a Targeted Mutation in Mice from Embryonic Stem Cell Chimeras or CRISPR-Cas Founders.Semantic proximity Read ↗

Genome-tagged mice (GTM): two sets of genome-wide congenic strains.Semantic proximity Read ↗

Strategies for Maintaining Mouse Mutations.Semantic proximity Read ↗

Technical approaches for mouse models of human disease.Semantic proximity Read ↗

Knockout mice: simple solutions to the problems of genetic background and flanking genes.Semantic proximity Read ↗

Effect of the genetic background on the phenotype of mouse mutations.Semantic proximity Read ↗

Whole-genome sequence of the C57L/J mouse inbred strain.Semantic proximity Read ↗

Generation, identification, and recovery of mouse mutations.Semantic proximity Read ↗

A targeted screen to detect recessive mutations that have quantitative effects.Semantic proximity Read ↗

Novel insights into the genetic background of genetically modified mice.Semantic proximity Read ↗

Using standard nomenclature to adequately name transgenes, knockout gene alleles and any mutation associated to a genetically modified mouse strain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.