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Efficient production of offspring from Japanese wild-derived strains of mice (Mus musculus molossinus) by improved assisted reproductive technologies.

Biology of reproduction - 1 May 2012

Hasegawa Ayumi, Mochida Keiji, Matoba Shogo, Yonezawa Kazuya, Ohta Akihiko, Watanabe Gen, Taya Kazuyoshi, Ogura Atsuo

Abstract excerpt

Because the genetic diversity of the laboratory mouse (Mus musculus) is very limited, wild-derived strains from this genus could provide invaluable experimental models for studies of mouse genetics and epigenetics such as quantitative trait locus analysis. However, such strains generally show poor reproductive performance under conventional husbandry conditions, so their use for large-scale analyses has been...

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PMID: 22337332
DOI: 10.1095/biolreprod.111.098491

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