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Article

Comprehensive Analysis of miRNome Alterations in Response to Sorafenib Treatment in Colorectal Cancer Cells.

International journal of molecular sciences - 1 Dec 2016

Pehserl Anna-Maria, Ress Anna Lena, Stanzer Stefanie, Resel Margit, Karbiener Michael, Stadelmeyer Elke, Stiegelbauer Verena, Gerger Armin, Mayr Christian, Scheideler Marcel, Hutterer Georg C, Bauernhofer Thomas, Kiesslich Tobias, Pichler Martin

Abstract excerpt

MicroRNAs (miRNAs) are master regulators of drug resistance and have been previously proposed as potential biomarkers for the prediction of therapeutic response in colorectal cancer (CRC). Sorafenib, a multi-kinase inhibitor which has been approved for the treatment of liver, renal and thyroid cancer, is currently being studied as a monotherapy in selected molecular subtypes or in combination with other drugs in...

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Identifiers

PMID: 27916938
DOI: 10.3390/ijms17122011
PMCID: PMC5187811

Genes

KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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