Article
Sorafenib induces growth suppression in mouse models of gastrointestinal stromal tumor.
Molecular cancer therapeutics - 1 Jan 2009
Huynh Hung, Lee Jonathan W J, Chow Pierce K H, Ngo Van Chanh, Lew Guo Bin, Lam Irene W L, Ong Hock Soo, Chung Alexander, Soo Khee Chee
Abstract excerpt
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. Current therapeutic options include surgery and targeted molecular approaches such as imatinib and sunitinib. Our aim was to establish patient-derived GIST xenografts for the use of screening new drugs and improving current treatment regimens used in GIST. In this present study, we investigate the antitumor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.