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Article

The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying.

PLoS genetics - 1 Dec 2016

Wang Shuaiyu, Jacquemyn Julie, Murru Sara, Martinelli Paola, Barth Esther, Langer Thomas, Niessen Carien M, Rugarli Elena I

Abstract excerpt

The m-AAA protease preserves proteostasis of the inner mitochondrial membrane. It ensures a functional respiratory chain, by controlling the turnover of respiratory complex subunits and allowing mitochondrial translation, but other functions in mitochondria are conceivable. Mutations in genes encoding subunits of the m-AAA protease have been linked to various neurodegenerative diseases in humans, such as...

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Identifiers

PMID: 27911893
DOI: 10.1371/journal.pgen.1006463
PMCID: PMC5135034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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