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Article

Autocatalytic processing of m-AAA protease subunits in mitochondria.

Molecular biology of the cell - 1 Oct 2009

Koppen Mirko, Bonn Florian, Ehses Sarah, Langer Thomas

Abstract excerpt

m-AAA proteases are ATP-dependent proteolytic machines in the inner membrane of mitochondria which are crucial for the maintenance of mitochondrial activities. Conserved nuclear-encoded subunits, termed paraplegin, Afg3l1, and Afg3l2, form various isoenzymes differing in their subunit composition in mammalian mitochondria. Mutations in different m-AAA protease subunits are associated with distinct neuronal...

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Share to Mitochondrial Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19656850
DOI: 10.1091/mbc.e09-03-0218
PMCID: PMC2754935

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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