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Article

In vivo detection of oxidized proteins: a practical approach to tissue-derived mitochondria.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Maltecca Francesca, Casari Giorgio

Abstract excerpt

Mitochondria are the major producers of free radical oxygen species (ROS) as well as the major target of oxidative damage. Defects in the mitochondrial respiratory chain complexes can increase ROS production and reduce ROS removal, leading to oxidative modification of proteins, lipids, and DNA. AAA proteases of the inner mitochondrial membrane, paraplegin and AFG3L2, participate in the biogenesis and maintenance...

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Identifiers

PMID: 20700718
DOI: 10.1007/978-1-60761-756-3_17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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