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Article

Par3L enhances colorectal cancer cell survival by inhibiting Lkb1/AMPK signaling pathway.

Biochemical and biophysical research communications - 22 Jan 2017

Li Taiyuan, Liu Dongning, Lei Xiong, Jiang Qunguang

Abstract excerpt

Partitioning defective 3-like protein (Par3L) is a recently identified cell polarity protein that plays an important role in mammary stem cell maintenance. Previously, we showed that high expression of Par3L is associated with poor survival in malignant colorectal cancer (CRC), but the underlying mechanism remained unknown. To this end, we established a Par3L knockout colorectal cancer cell line using the...

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Identifiers

PMID: 27908725
DOI: 10.1016/j.bbrc.2016.11.154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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