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Article

Partition-Defective 3 (PARD3) Regulates Proliferation, Apoptosis, Migration, and Invasion in Esophageal Squamous Cell Carcinoma Cells.

Medical science monitor : international medical journal of experimental and clinical research - 20 May 2017

Wang Lei, Zhang Haiping, Hasim Ayshamgul, Tuerhong Abuduaini, Hou Zhichao, Abdurahmam Ablajan, Sheyhidin Ilyar

Abstract excerpt

BACKGROUND Altered expression of partition-defective 3 (PARD3), a polarity-related gene associated with oncogenesis, has been identified in some cancers, but the role of PARD3 in esophageal squamous cell carcinoma (ESCC) remains unclear. MATERIAL AND METHODS PARD3 expression in Eca109 cells was silenced using siRNA and overexpressed using an expression vector. We investigated the role of PARD3 in ESCC growth and...

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Share to Adaptor Proteins, Signal Transducing
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

Share to Gene Silencing

Share to Neoplasm Invasiveness

Share to RNA, Small Interfering

Source

Open in PubMed Open full text

Identifiers

PMID: 28526815
DOI: 10.12659/msm.903380
PMCID: PMC5446977

Genes

PARD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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