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Article

Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.

Gastroenterology - 1 Jul 2010

Roberts Kari E, Kawut Steven M, Krowka Michael J, Brown Robert S, Trotter James F, Shah Vijay, Peter Inga, Tighiouart Hocine, Mitra Nandita, Handorf Elizabeth, Knowles James A, Zacks Steven, Fallon Michael B

Abstract excerpt

BACKGROUND & AIMS: Hepatopulmonary syndrome (HPS) affects 10%-30% of patients with cirrhosis and portal hypertension and significantly increases mortality. Studies in experimental models indicate that pulmonary angiogenesis contributes to the development of HPS, but pathogenesis in humans is poorly understood. We investigated genetic risk factors for HPS in patients with advanced liver disease. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20346360
DOI: 10.1053/j.gastro.2010.03.044
PMCID: PMC2908261

Genes

CAV3
ENG
RUNX1
ESR2
NOX4
TIE1
VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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