Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of IDH and NAT2 gene polymorphisms in acute myeloid leukemia risk and overall survival in an Arab population: A case-control study.

PloS one - 1 Jan 2023

Al-Khatib Sohaib M, Ababneh Obada, Abushukair Hassann, Abdo Nour, Al-Eitan Laith N

Abstract excerpt

Acute myeloid leukemia (AML) is a malignancy of the myeloid cells due to the clonal and malignant proliferation of blast cells. The etiology of AML is complex and involves environmental and genetic factors. Such genetic aberrations include FLT3, DNMT3, IDH1, IDH2, NAT2, and WT. In this study, we analyzed the relationship between five, not previously studied in any Arab population, single nucleotide polymorphisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabs
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Isocitrate Dehydrogenase

Share to Leukemia, Myeloid, Acute

Share to Nucleophosmin

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 37478088
DOI: 10.1371/journal.pone.0289014
PMCID: PMC10361469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of IDH and NAT2 gene polymorphisms in acute myeloid leukemia risk and overall survival in an Arab population: A case-control study.PMID 37478088Read ↗

Prevalence and Clinical Effect of IDH1 and IDH2 Mutations Among Cytogenetically Normal Acute Myeloid Leukemia Patients.Semantic proximity Read ↗

IDH1/2 mutations in acute myeloid leukemiaSemantic proximity Read ↗

A case-control study in NAT2 gene polymorphism studies in patients diagnosed with acute myeloid leukemia.Semantic proximity Read ↗

Genetic Polymorphism Study of IDH 1/2 and TET2 Genes in Acute Myeloid leukemia Patients.Semantic proximity Read ↗

Molecular Evaluation of DNMT3A and IDH1/2 Gene Mutation: Frequency, Distribution Pattern and Associations with Additional Molecular Markers in Normal Karyotype Indian Acute Myeloid Leukemia PatientsSemantic proximity Read ↗

Genetic polymorphisms of NAT2 and risk of acute myeloid leukemia: A case-control study.Semantic proximity Read ↗

Differential impact of IDH1/2 mutational subclasses on outcome in adult AML: results from a large multicenter study.Semantic proximity Read ↗

Investigation of Isocitrate Dehydrogenase 1 and 2 Mutations in Acute Leukemia Patients in Saudi Arabia.Semantic proximity Read ↗

Genomic Landscape of Acute Myeloid Leukemia in a mixed African Cohort: A Pilot StudySemantic proximity Read ↗

DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies.Semantic proximity Read ↗

[Prognostic significance of different IDH mutations and accompanying gene mutations in patients with acute myeloid leukemia].Semantic proximity Read ↗

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.